Does Benadryl work like Xanax?
Does Benadryl work like Xanax? However, OTC antihistamines (i.e., Benadryl/diphenhydramine) have been recommended as a short-term solution for anxiety symptoms. While there is likely not any harm in taking an occasional OTC antihistamine as an over-the-counter Xanax alternative, the sedating side effects are not ideal for regular use.
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